Unlock deep metabolic insights with high-throughput, targeted metabolomics. Ensure reproducibility, sensitivity, and accuracy for biomarker measurements, clinical research, and drug development.
Targeted metabolomics is a quantitative approach to identifying and measuring specific, known metabolites in biological samples using advanced analytical techniques such as LC-MS/MS and GC-MS.
This approach focuses on pre-determined molecules, allowing for precise quantification and high sensitivity.
Aspect | Targeted | Untargeted |
---|---|---|
Focus | Known metabolites | Global profiling |
Quantification | Absolute | Relative |
Sensitivity | Very high | Moderate |
Coverage | Selected metabolites | Broad spectrum |
Analysis Time | Faster | Longer |
Data Processing | Streamlined | Complex |
Application | Hypothesis-driven research | Discovery-based research |
Complete profiling of lipid species including phospholipids, sphingolipids, and neutral lipids
Quantification of proteinogenic and non-proteinogenic amino acids, including derivatives and metabolite
Glycolysis, TCA cycle, and pentose phosphate pathway intermediates
Comprehensive profiling of gut microbiome-derived SCFAs including acetate, propionate, butyrate, and branched-chain derivatives
Endocrine system metabolites including sex hormones, glucocorticoids, and mineralocorticoids
Comprehensive neurotransmitter quantification including catecholamines, serotonin, and related metabolites
Detailed profiling of primary and secondary bile acids with complete specification of quantified and semi-quantified molecules
Tailored solutions for specific research needs based on your unique requirements
We maintain an extensive in-house library of authenticated standards for absolute quantification of the metabolites; our platform can accommodate quantification of virtually any metabolite provided a suitable analytical standard is available. We routinely expand our capabilities based on research demands and can work with you to develop custom quantification methods for novel or specialized metabolites of interest to your research.
Our state-of-the-art facility houses the latest analytical platforms, including state-of-the-art LC-
MS/MS and GC-MS systems. What sets us apart is our unique ability to seamlessly integrate
targeted and untargeted metabolomics approaches, providing comprehensive metabolic insights
that other providers might miss. Our custom method development capabilities ensure that each
project receives a tailored analytical approach, while our flexible research methodology allows
us to adapt as your research evolves and new questions arise.
In the clinical research sphere, measuring specific metabolites enables deeper understanding of disease mechanisms. Our biomarker validation studies help transform promising candidates into clinically useful diagnostic tools. We support treatment monitoring with precise, quantitative measurements of relevant metabolites, enabling researchers to track therapeutic effectiveness with highest accuracy. In precision medicine, detailed metabolic analyses help identify patient subgroups and optimize treatment strategies based on individual metabolic profiles.
Targeted metabolomics plays a crucial role in modern drug development. We support pharmaceutical companies throughout the drug development pipeline, from early-stage discovery to clinical trials. Measuring drug metabolites provides critical insights into drug metabolism and effectiveness, while our biomarker discovery platform helps identify novel drug targets and monitor treatment responses. Safety assessment studies benefit from our highly sensitive analytical methods, enabling the detection of subtle metabolic changes that might indicate potential adverse effects.
We help researchers understand the metabolic impact of different diets, nutrients, and supplements. Our detailed analysis of food components and their metabolic effects supports the development of improved nutritional guidelines and functional foods.
The metabolomics provides the foundation for personalized medicine approaches by characterizing individual metabolic phenotypes. This allows for targeted interventions based on specific metabolic patterns and supports the development of patient-specific treatment strategies.
Our services enable detailed understanding of xenobiotic metabolism and toxic effects at the molecular level. Environmental researchers use our platforms to track metabolic changes in response to various environmental stressors, pollutants, and climate conditions.
Raw data undergo rigorous processing using our advanced pipeline:
Once your project begins, samples undergo processing in our state-of-the-art facility:
Sample analysis is performed on our state-of-the-art platforms:
Our collaboration begins with a thorough consultation to understand your research objectives.
Report Delivery & Expert Consultation